The National Center for Medical Home Implementation (NCMHI or National Center) launched the Innovative and Promising Practices in Medical Home Implementation Initiative (Promising Practices) in 2015. This initiative provides opportunities for pediatric medical home projects, programs, and practices from across the United States to share implementation strategies. These strategies enhance the delivery of primary care services for children and youth, particularly those with special health care needs and those living in medically underserved communities. The Promising Practices profiles on the National Center Web site provide practical, replicable implementation strategies and tools for other interested in advancing the medical home model. This e-Newsletter provides tools, resources, and strategies to support innovative and promising practices in pediatric medical home implementation.